Our bones are constantly being renewed, but as we age, this process slows down. In those with Osteoporosis, the process of bone renewal is reduced, so bones become weak and brittle over time. With advanced osteoporosis, even simple everyday activities can lead to bone fractures.  Women are at higher risk for osteoporosis. While estrogen helps women maintain bone density, the drop in estrogen at menopause may lead to bone loss.